Thursday 31 July 2014

Active elements of Broad Spectrum Anti-Viral

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Combating viruses is much more difficult than fighting bacteria. So far there has been no active elements such as broad-spectrum anti-viral antibiotics.
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The most effective method of combating the virus is by immunization. But the efficacy of the vaccine is usually only limited to certain viruses. Now researchers from the Massachusetts Institute of Technology - MIT in the United States are testing a type of active elements, which in laboratory experiments able to crush a variety of viruses.

The new active element was named Draco. In laboratory trials, the active ingredient proven very powerful crush Draco virus. Dr.Todd Rider senior researcher from the Massachusetts Institute of Technology - MIT expects, active elements can be a powerful combat all types of viruses.
[The swine flu virus H1N1]

 
H1N1 swine flu virus

"We mengujicobanya against 15 viruses, including influenza virus, H1N1 swine flu, gastrointestinal flu virus, polio and dengue virus. The medicine is effective against all viruses. We still have a list of a number of viruses, which we want to test. We expect Draco in general can help against all viruses, "he said.

Cells Attacking Pain

Active element Draco did not attack the virus directly, but targeting the viral host cells. In the sense of body cells that have been infected by the virus.

Rider explains the mechanism: "Viruses multiply in the host cell and then kills the cell. The virus out of the cell and the next cell attack. Draco destroy cells infected first, before the virus to multiply in the cells and can infect other cells. "
[The study of the HIV virus in the laboratory.]

 
HIV virus in laboratory research.

Draco can track directionally cells infected with a virus. How to track down "Ribo Nucleic Acid" - RNA in the patient's body. Researchers know, if viruses multiply in the cells, will form an extra-long double-stranded RNA. In normal conditions, will not form an extra long double chain RNA in the cells of the body. So the extra-long RNA chain, is an indication that the virus attacks the cell.

Ridder added: "Draco recognize infected cells, which contained RNA virus. Draco active element triggering the cells to destroy themselves, and in that way the infection is eradicated. Draco does not attack healthy cells and only attack the infected cells. "

Dr. Todd Rider and his team of researchers at Lincoln Laboratory, Massachusetts Institute of Technology - MIT, most do not prove that such a function Draco. It was demonstrated in vitro, in which a cell infected by a virus different. The MIT research team also managed to cure mice infected by the H1N1 swine flu virus. Rider believes, Draco is an active ingredient for the manufacture of a universal remedy against virus attacks, powerful combat the flu virus to smallpox virus.

Deadly impact

However, other researchers observed with a more critical research conducted at the Massachusetts Institute of Technology - MIT TSB. Andrea Branch of the Mount Sinai medical school in New York warned: "Description of the paper is very smart, I appreciate the creativity of the work of fellow researchers. But, suggesting that it functions in a cell in vitro or in mice, is a different matter. Until a cure is developed for humans is still very far away. "
[Hepatitis B virus]

 
Hepatitis B virus

In addition, the method also invite risk. Andrea Branch microbiologists revealed: "If a great deal of virus-infected cells and supposing forced to commit suicide, the impact will kill the patient. Indeed there is infection, which is only a few cells attack the body. If Draco kill cells, may function healing. But the Hepatitis-B infection, for example, most of the infected liver cells, and if these cells are killed, then the patient's liver will malfunction. Without a liver transplant, the patient will not live. This is the danger of attacking the cells and not the virus. "

But Todd Rider and his team at the Massachusetts Institute of Technology - MIT to continue his research. They expect, in the next stage, Draco can be tested against Ebola virus and HIV.